I agree, I have a good amount of scholarly sources to use and cite in my paper. But one more won't hurt. After all, more is better than less. More sources just means more to support my paper and make it more of a solid piece. As long as I am not just filling the paper with quotes, paraphrases and citations, and am making a strong clear argument, it should not serve much of a problem.
So one last scholarly source for this blog.
"Animal models of human amyloidoses: Are transgenic mice worth the timeand trouble?" by Joel N. Buxbaum may just be the source that will answer some of your questions as to whether or not transgenic animals as great as they are perceived to be. Many of the sources I use mainly focus on the benefits that modeled animals have towards research. Some do address problems and disadvantages they faced, but the main tone of the paper is praising the mice.
However, Buxbaum's source focuses on whether or not transgenic animals are actually worth it. Should they be used? Are they really that much better? Is the trade-off so significant?
In this paper, Buxbaum gives several examples of where transgenic models are used for and what types of considerations might be required for an ideal transgenic model. Buxbaum's tone is not a complete go-for-it nor a skeptical one. Rather, Buxbaum is openminded since he listed some considerations for transgenic animals. He then concluded the paper by saying it is up to the researchers as to whether or not it is worth using transgenic animals. The advantage to using transgenic models is being able to examine certain effects and singling out one protein to study. The results of using transgenic models and using non-transgenic models really varies from certain disorders and specifics of the disorder. The disadvantage to using transgenic mice is the unexplainable results, such as a enormous loss of cells. This may be because of the mice's short life span and the fact that mice are much simpler animals than humans, but that is not known for sure. There are always pros and cons to making a decision, but in the end, it remains to be the researchers' decision as to whether or not it is suitable for use in their specific research problem.
I feel that this source is a great mediator to my paper since my other sources are quite favorable towards using transgenic animals. It is always great to have a source that is not too one sided.
However, Buxbaum's source focuses on whether or not transgenic animals are actually worth it. Should they be used? Are they really that much better? Is the trade-off so significant?
In this paper, Buxbaum gives several examples of where transgenic models are used for and what types of considerations might be required for an ideal transgenic model. Buxbaum's tone is not a complete go-for-it nor a skeptical one. Rather, Buxbaum is openminded since he listed some considerations for transgenic animals. He then concluded the paper by saying it is up to the researchers as to whether or not it is worth using transgenic animals. The advantage to using transgenic models is being able to examine certain effects and singling out one protein to study. The results of using transgenic models and using non-transgenic models really varies from certain disorders and specifics of the disorder. The disadvantage to using transgenic mice is the unexplainable results, such as a enormous loss of cells. This may be because of the mice's short life span and the fact that mice are much simpler animals than humans, but that is not known for sure. There are always pros and cons to making a decision, but in the end, it remains to be the researchers' decision as to whether or not it is suitable for use in their specific research problem.
I feel that this source is a great mediator to my paper since my other sources are quite favorable towards using transgenic animals. It is always great to have a source that is not too one sided.
